International journal of current research, ijcr is an international double blinded referred and peerviewed monthly online academic research journal in all the streams. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years. Journal impact factor list 2016 2015 2014 citefactor. After its discovery by carl vogt in 1842, apoptosis research was dormant for more than a century. Journal of molecular signaling encompasses all the molecular aspects of cell signaling involving receptors, gproteins, kinases, phosphatases, and transcription factors in regulating cell proliferation, differentiation, apoptosis, and oncogenesis in mammalian cells.
Journal metrics impact factor 2015 journal impact factors are published each summer by thomson reuters via journal citation reports. Papers published in high impact journal international journal of pharmacy collect about 4 fold citations as do virtually identical articles published in journals with lower impact ratings. It is also one of the most studied topics among cell biologists. Clinical apoptosis impact factoromics international. Europe pmc xchromosomelinked inhibitor of apoptosis as a key factor for chemoresistance in clear cell carcinoma of the ovary. Microrna1295p affects immune privilege and apoptosis of nucleus pulposus cells via regulating fadd in intervertebral disc degeneration. Cellular signalling aims at full length research papers defining signalling systems ranging from microorganisms to cells, tissues and higher organisms. The role of hypoxia inducible factor 1 hif 1 in hypoxia induced apoptosis. Inappropriate apoptosis either too little or too much is a factor in many human conditions including neurodegenerative diseases, ischemic damage, autoimmune disorders and many types of cancer.
While tumor necrosis factor tnf related apoptosisinducing ligand trail is a promising new agent for the treatment of cancer, resistance to trail remains a therapeutic challenge. First apoptosis signal fas, caspases are the factors that promote apoptosis whereas bcl2 inhibits apoptosis. Apoptosis impact factoromics internationaljournal of cell. Open journal of apoptosis ojapo is an openly accessible journal published quarterly. Apoptosis impact factor the impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. Department of spine surgery, tongji hospital, tongji university school of medicine, shanghai 200065, china. The prognostic value may differ between various histological tumour types from different organs. Youre seeing our new journal sites and wed like your opinion, please send feedback. The fas ligand fasl is a member of the tnf family, and induces apoptosis in fasbearing cells. It aims to stimulate research on the basis of mechanisms of apoptosis and on its role in various human disease processes including. Welcome to ijcr international journal of current research.
Bax translocated into mitochondria, a reduction in m was observed and a release of cytochrome c and apoptosis inducing factor aif from mitochondria into the. The journal is devoted to the rapid publication of innovative basic and clinicallyoriented. Free download, read and cite papers for your scientific research and study. Differentiation of eukaryotes at the molecular level and the use of transgenic and targeted mutagenesis approaches to problems of differentiation are of particular interest to the journal. Apoptosis is considered a vital component of various processes including normal cell turnover, proper development and functioning of the immune system, hormonedependent atrophy. It shows an average citation rate per article for the past 2 years. The two years line is equivalent to journal impact factor thomson reuters. Apoptosis is a type of cell death that plays an important role in early development and growth of normal adult tissues. Cell death is a vital process of the cell to maintain the ratio of the cells such as cell movement. Apoptosis impact factor, if, number of article, detailed information and journal factor. Rispetto allo storico impact factor, l impact factor 2018 di apoptosis. The process of programmed cell death, or apoptosis, is generally characterized by distinct morphological characteristics and energydependent biochemical mechanisms. Neoplasm or neoplasia refers to the rapid, uncontrolled and abnormal growth of cells or tissues in the body. In certain cases, unusual behavior of cell is observed, which is termed as neoplasm.
Cells that do are eliminated right away by apoptosis. Polyphenolrich extract induces apoptosis with immunogenic. In this large, retrospective cohort study from an area with high prevalence of hbv infection, the authors demonstrated that hbsag was an independent unfavorable factor significantly associated with survival, highlighting its potential as a novel prognostic indicator to improve the risk stratification of patients with dlbcl in the rituximab era. This study is aimed to evaluate the relationship between the severity of apoptotic and autophagic cell death based on the distribution of brucella spp. Apoptosis impact factoromics internationaljournal of. Apoptosis programmed cell death is a systematic and coordinated cellular process that occurs in physiological and pathophysiological conditions. Their ability to reduce cancer incidence in these studies is likely related to apoptosis. Clinical apoptosis articles are accessible to all the readers that are published online. Age impact factor, if, number of article, detailed information and journal factor. The objective of this study was to evaluate the prognostic effect of the apoptosis regulators p53, bax and puma for recurrent disease and diseasefree survival dfs in a series of 105 patients in figostages iii with epithelial ovarian cancer, all. Apoptosis inducing factor aif is a protein that triggers chromatin condensation and dna fragmentation in a cell in order to induce programmed cell death. Apoptosis inducing factor aif is a small protein that resides normally within the intermembrane space of mitochondria, and upon certain death stimuli translocates into the cytosol and ultimately the nucleus where it contributes to dna fragmentation and chromatin condensation.
Europe pmc is an archive of life sciences journal literature. Journal citation reports clarivate analytics, 2019 5year impact factor. Detection kits were used to evaluate the levels of tumor necrosis factor tnf, interleukin il. The h5 index therefore cannot be dominated by one or several highly cited articles. Journal of cell science and apoptosis discusses the latest research innovations and. It is regulated by physiological stimuli and is present in many species and tissues. The total number of times that a journal was cited by all thomson reuters indexed journals in 2017. Apoptosis induced by a death factor md anderson cancer center. Apoptosis, also called programmed cell death, has attracted great attention in recent years. Impact factor of journal apoptosis 2016 2015 2014 impact. Apoptosis also plays an essential role in the development and maintenance of a healthy immune system. Journal of cell science and apoptosis open access journals. The two years line is equivalent to journal impact factor thomson reuters metric. Overexpression of apoptosis inducing factor aggravates.
Apoptosis is considered a vital component of various processes including normal cell turnover, proper development and functioning of the immune system. The impact factor is a metric whose use is debated. This scientific journal focuses on the recognition of cellular responses to dna damage, apoptosis cell death, and inactivation of tumor suppressor genes and analysis of the carcinogenic process by genetic and epigenetic alterations in genes for. Apoptosis inducing factor is involved in initiating a caspaseindependent pathway of apoptosis positive intrinsic regulator of apoptosis by causing dna fragmentation and chromatin condensation. Differentiation is a multidisciplinary journal dealing with topics relating to cell differentiation, development, cellular structure and function, and cancer. Aaf from incomplete carcinogens, the rate of cell death apoptosis and cell. When b and t cells immune cells that bind specific molecules are first produced, theyre tested to see if they react against any of the bodys own self components.
Compared with historical impact factor data, the impact factor 2018 of apoptosis. Impact of taurine on the proliferation and apoptosis of huma. Apoptosis is the process of programmed cell death which usually occur in multicellular organisms and the biochemical events lead to characteristic cell. Apoptosis is morphologically described by chromatin buildup and dna corruption, and is a component utilized by the resistant framework for antigenimpelled clonal erasure of cortical thymocytes.
This is the compelling advantage of open access journals, such as cells. Polyphenolrich extract induces apoptosis with immunogenic markers in melanoma cells through the er stressassociated kinase perk. Icariin inhibits endoplasmic reticulum stressinduced. Apoptosis list of high impact articles ppts journals videos. Because any single criterion for apoptosis may produce false negative or positive results, apoptosis should always be assessed by multiple criteria table 3. In apoptosis, the early changes involve cell shrinkage, cytosolic shrinkage, more marked chromatin clumping, cytoplasmic blebbing, swollen er on occasion, and mitochondria that are normal or condensed. Apoptosis list of high impact articles ppts journals. This mechanism allows organisms to get rid of cells that are no longer needed or have become dangerous. The procedure of programmed cell death, or apoptosis, is by and large portrayed by particular morphological qualities and vitality subordinate biochemical components. Indeed, mice bearing a hypomorphic mutation causing. Impact of taurine on the proliferation and apoptosis of human cervical. Animate thing ligands cytokines, growth factors, hormones, neurotransmitters, or cell. Rispetto allo storico impact factor, limpact factor 2018 di apoptosis. It aims to stimulate research on the basis of mechanisms of apoptosis and on its role in various human disease processes.
Xchromosomelinked inhibitor of apoptosis as a key factor. We also detected a cytosolic increase of apoptosis inducing factor aif, a trigger of caspaseindependent apoptosis. Integrative cancer research is a multidisciplinary journal that brings together all the varied aspects of research that will ultimately lead to the prevention of cancer in man. Apoptosis article developmental biology khan academy. Funding information that explains whether and by whom the research was supported. Full details of the journal s subject coverage and editorial policies can be found here. Mg2, a proteasome inhibitor, induces apoptosis in tumor. Cell proliferation is an open access journal devoted to studies into all aspects of cell proliferation and differentiation in normal and abnormal states. This special issue of cells is dedicated to apoptosis. Impact factors and ranking data are presented for the preceding calendar year. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field.
N2 fas is a type i membrane protein belonging to the tnf receptor family. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. Exposure to cellular stress can trigger the p53 tumor suppressor, a sequencespecific transcription factor, to induce cell growth arrest or apoptosis. Apoptosis is a form of programmed cell death, or cellular suicide. Deregulation of apoptosis is a major contributing factor in the development of many diseases. The epidermal growth factor receptor egfr is overexpressed in the majority of. Metformin induces apoptosis and inhibits proliferation through the ampactivated protein kinase and insulinlike growth factor 1 receptor pathways in the bile duct cancer cells. Apoptosis is an orderly process in which the cells contents are packaged into small packets of membrane for garbage collection by immune cells. The prognostic impact of hypoxia related apoptosis is not yet clear.
The role of hypoxia inducible factor 1 hif1 in hypoxia. Apoptosis rg journal impact rankings 2018 and 2019. Wikijournal of medicinecitation metrics wikiversity. Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and pathological conditions. The impact factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. If a journal publishes 100 articles sooner, an h5 index can be calculated earlier. Journal citation reports clarivate analytics, 2019.
As such, it is a process of deliberate life relinquishment by an unwanted cell in a multicellular organism. Apoptosis is an essential process for multicellular organisms. Haotian li 1,2, xinran zhang 3, xi qi 1,2, xu zhu 1,2, liming cheng 1,2. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of apoptosis.
Tmp alleviated the effects of lps on cell viability, inflammation levels and cell apoptosis. Cellular signalling publishes original research describing fundamental and clinical findings on the mechanisms, actions and structural components of cellular signalling systems in vitro and in vivo. Its rediscovery in the second half of this century, and the coining of the term apoptosis in 1972 by kerr, wyllie, and currie, ignited an unparalleled interest in this field of science. Neoplasm journals insight medical publishing open access. They consist of a short collection of bullet points that convey the core findings of the article and should be submitted in a separate file in the online submission system. The ability to modulate the life or death of a cell is recognized for its immense therapeutic potential. Sidestepping or resisting apoptosis is a distinct characteristic of human cancers including childhood malignancies. Tetramethylpyrazine reduces inflammation levels and the. The main morphological characteristics are nuclear fragmentation and cellular breakdown in apoptotic vesicles. An understanding of the underlying mechanism of apoptosis is important as it plays a pivotal role in the pathogenesis of many diseases. Another aif function is to regulate the permeability of the. Impact of ambient particulate matter on the dna methylation of. Icariin inhibits endoplasmic reticulum stressinduced neuronal apoptosis after spinal cord injury through modulating the pi3kakt signaling pathway.
Peteranderl c and herold s 2017 the impact of the interferontnfrelated apoptosis inducing ligand signaling axis on disease progression. The chart shows the evolution of the average number of times documents published in a journal in the past two, three and four years have been cited in the current year. All journal articles featured in cell cycle vol 19 issue 8. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of. The role of apoptosis and autophagy in bovine abortions. The choice between these cellular responses is influenced by many factors, including the type of cell and stress, and the action of p53 coactivators. Regulation of the tissue factor isoform expression and thrombogenicity of hmec1 by.
In some, the problem is due to too much apoptosis, such as in the case of. Apoptosis high impact list of articles ppts journals 1053. Apoptosisinducing factor an overview sciencedirect topics. May 17, 2018 in biology, apoptosis is one of the main types of programmed cell death pcd. It aims to stimulate research on the basis of mechanisms of apoptosis and on its. Intraventricular medium b treatment benefits an ischemic. For example, apoptosis inducing factor aif promotes dna degradation in a caspaseindependent fashion lorenzo and susin 2007. Following cell death, both types undergo postmortem changes collectively termed necrosis. Jan 30, 2020 apoptosis inducing factor aif has been shown to be a major contributor to neuron loss in the immature brain after hypoxiaischemia hi.